Wednesday, December 3, 2008

Downstream processing of biobased succinic acid (4)

Approach IV: Reactive Extraction-Based SA Purification: Extraction and Crystallization (Huh, et al. Process Bio. 41(2006)1461-1465



Key points for the process

  • TOA has high extractability and used for selective removal of contaminated organic acids and salts from dilute fermentation broth
    --Only extract the undissociated form of carboxylic acids
    -- Need multistage extraction using different degrees of dissociation of each acid with pH

  • Vacuum distillation
    --Concentrate the pretreated broth and remove volatile organic acids such as acetic acid, formic acid etc.

  • Crystallization
    --The crystal of SA is formed more than other organic acids in saturated fermentation broth (after vacuum distillation) and low solubility

Any comments for this method? Advantages and disadvantages? Cost or simplexity?


2 comments:

Teguh Yulianto said...

nice article and topic your blog, this some solve to reduce about global warming.

Onedrop said...

Thanks for your comments and encouraging. I will blog more about sugar-based chemicals and related issues.