Wednesday, November 19, 2008

Superactive cellulase formulation using cellobiohydrolase-1 from Penicillium funiculosum

A new patent (US 7,449,550) was assigned to Alliance for Sustainable Energy LLC for the new invention on developing a superactive cellulase formulation using cellobiohydrolase-1:

"Purified cellobiohydrolase I (glycosyl hydrolase family 7 (Cel7A) enzymes from Penicillium funiculosum demonstrate a high level of specific performance in comparison to other Cel7 family member enzymes when formulated with purified EIcd endoglucanase from A. cellulolyticus and tested on pretreated corn stover. This result is true of the purified native enzyme, as well as recombinantly expressed enzyme, for example, that enzyme expressed in a non-native Aspergillus host. In a specific example, the specific performance of the formulation using purified recombinant Cel7A from Penicillium funiculosum expressed in A. awamori is increased by more than 200 percent when compared to a formulation using purified Cel7A from Trichoderma reesei."

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