Almost all of currently reported biomass pretreatments are those reqyiring post- liquor/solid separation or washing, or nutralization, or even detoxification before further processing (hydrolysis), which will add additional cost due to the more step unit operations. A cost-effective pretreatment should be low demand of post- pretreatment processing. A "whole slurry" processing or hydrolysis will be ideal case. Therefore, the pretreatment should not be to acidic or too basic, or too harsher that generate too much toxic compounds. I am working on a process that really can realize this goal.
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